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Robert P Schleimer Selected Research

Rhinosinusitis

11/2022Use of intraoperative frontal sinus mometasone-eluting stents decreased interleukin 5 and interleukin 13 in patients with chronic rhinosinusitis with nasal polyps.
11/2022Retinoic acid promotes fibrinolysis and may regulate polyp formation.
1/2022Studies on activation and regulation of the coagulation cascade in chronic rhinosinusitis with nasal polyps.
1/2022Efficacy of an oral CRTH2 antagonist (AZD1981) in the treatment of chronic rhinosinusitis with nasal polyps in adults: A randomized controlled clinical trial.
1/2022Anti-phospholipid antibodies are elevated and functionally active in chronic rhinosinusitis with nasal polyps.
1/2022Regulation of the Expression of SARS-CoV-2 Receptor Angiotensin-Converting Enzyme 2 in Nasal Mucosa.
10/2021Epithelial-Cell-Derived Extracellular Vesicles in Pathophysiology of Epithelial Injury and Repair in Chronic Rhinosinusitis: Connecting Immunology in Research Lab to Biomarkers in Clinics.
9/2021Impact of type 2 targeting biologics on acute exacerbations of chronic rhinosinusitis.
1/2021Mechanisms and biomarkers of inflammatory endotypes in chronic rhinosinusitis without nasal polyps.
1/2021Activation of the 15-lipoxygenase pathway in aspirin-exacerbated respiratory disease.
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Robert P Schleimer Research Topics

Disease

59Rhinosinusitis
11/2022 - 12/2004
56Nasal Polyps (Nasal Polyp)
11/2022 - 06/2008
37Inflammation (Inflammations)
01/2022 - 01/2002
34Asthma (Bronchial Asthma)
01/2022 - 01/2002
12Polyps
11/2022 - 03/2006
8Infections
01/2021 - 01/2005
6Virus Diseases (Viral Diseases)
01/2021 - 07/2007
5Hypersensitivity (Allergy)
01/2022 - 05/2009
4Eosinophilia
11/2017 - 01/2009
4type 2C Congenital disorder of glycosylation
01/2015 - 03/2008
3Edema (Dropsy)
01/2020 - 01/2013
3Communicable Diseases (Infectious Diseases)
01/2018 - 01/2005
3Airway Remodeling
04/2015 - 06/2012
2Bronchiectasis
01/2022 - 12/2019
2Fibrosis (Cirrhosis)
01/2021 - 04/2014
2Pneumonia (Pneumonitis)
01/2021 - 07/2017
2Anosmia
11/2019 - 07/2016
2Food Hypersensitivity (Food Allergy)
01/2019 - 01/2009
2Allergic Rhinitis
01/2017 - 01/2016
2Gastroesophageal Reflux (GERD)
01/2016 - 05/2013
2Chronic Obstructive Pulmonary Disease (COPD)
12/2015 - 01/2005
2Hyperplasia
04/2014 - 06/2012
2Respiratory Hypersensitivity
04/2014 - 06/2012
2Anaphylaxis (Anaphylactic Shock)
01/2013 - 01/2009
2Necrosis
10/2010 - 03/2008
1Antiphospholipid Syndrome (Antiphospholipid Antibody Syndrome)
01/2022
1Thrombosis (Thrombus)
01/2022

Drug/Important Bio-Agent (IBA)

15CytokinesIBA
01/2022 - 01/2004
15Messenger RNA (mRNA)IBA
01/2022 - 11/2004
15Proteins (Proteins, Gene)FDA Link
01/2022 - 11/2004
13Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
01/2021 - 07/2011
10AntibodiesIBA
01/2022 - 12/2011
9FibrinIBA
11/2022 - 01/2013
9Biomarkers (Surrogate Marker)IBA
01/2022 - 03/2012
9Immunoglobulin E (IgE)IBA
01/2021 - 09/2008
9AllergensIBA
01/2019 - 09/2008
8ChemokinesIBA
01/2013 - 01/2004
7Adrenal Cortex Hormones (Corticosteroids)IBA
01/2022 - 02/2003
7GlucocorticoidsIBA
01/2017 - 01/2002
6Interleukin-13IBA
11/2022 - 08/2008
6Interleukin-6 (Interleukin 6)IBA
01/2021 - 03/2008
6LigandsIBA
01/2017 - 07/2010
5Immunoglobulin G (IgG)IBA
01/2022 - 09/2008
5Anti-Bacterial Agents (Antibiotics)IBA
01/2021 - 05/2009
5Complement System Proteins (Complement)IBA
01/2021 - 01/2005
5Thymic Stromal LymphopoietinIBA
01/2020 - 07/2007
5EnzymesIBA
11/2017 - 01/2004
4Plasminogen Activators (Plasminogen Activator)IBA
11/2022 - 06/2012
4Interleukin-5 (Interleukin 5)IBA
11/2022 - 01/2017
4Tissue Plasminogen Activator (Alteplase)FDA Link
01/2022 - 01/2013
4AutoantibodiesIBA
01/2022 - 12/2011
4Cyclooxygenase 1IBA
01/2021 - 07/2017
4Toll-Like Receptors (Toll-Like Receptor)IBA
10/2010 - 12/2004
3Interleukin-4 (Interleukin 4)IBA
01/2022 - 03/2008
3Interleukin-17 (Interleukin 17)IBA
01/2022 - 02/2010
3Pattern Recognition ReceptorsIBA
01/2021 - 01/2006
3Blood Proteins (Serum Proteins)IBA
01/2020 - 01/2013
3Immunoglobulins (Immunoglobulin)IBA
01/2018 - 06/2008
3ImmunosorbentsIBA
11/2017 - 10/2010
3LipopolysaccharidesIBA
01/2017 - 07/2010
3Fluticasone (Cutivate)FDA LinkGeneric
01/2014 - 01/2002
3AntigensIBA
04/2013 - 04/2005
2Mometasone Furoate (Nasonex)FDA LinkGeneric
11/2022 - 01/2002
2Tretinoin (Retinoic Acid)FDA LinkGeneric
11/2022 - 01/2022
2OvalbuminIBA
01/2022 - 01/2016
2Eosinophil Cationic ProteinIBA
01/2022 - 11/2017
2ORALIT (ORS)IBA
01/2022 - 01/2016
2Peptide Hydrolases (Proteases)FDA Link
01/2021 - 01/2020
2Tryptases (Tryptase)IBA
01/2020 - 08/2012
2Pharmaceutical PreparationsIBA
01/2019 - 02/2010
2Chemokine CCL26IBA
01/2017 - 11/2004
2ErbB Receptors (EGF Receptor)IBA
01/2017 - 04/2015
2Dexamethasone (Maxidex)FDA LinkGeneric
01/2017 - 02/2013
2Sialic Acid Binding Immunoglobulin-like LectinsIBA
02/2016 - 03/2015
2Enterotoxins (Enterotoxin)IBA
01/2016 - 01/2009
2S100 Proteins (S 100 Protein)IBA
11/2015 - 03/2010
2Factor XIII (Coagulation Factor XIII)IBA
09/2015 - 09/2013
2Plasminogen Activator Inhibitor 1IBA
01/2015 - 06/2012
2Substance PIBA
01/2014 - 10/2010
2Interleukin-1 (Interleukin 1)IBA
07/2012 - 07/2011
2Immunoglobulin A (IgA)IBA
12/2011 - 06/2008
2B-Cell Activating FactorIBA
12/2011 - 06/2008
2InterleukinsIBA
10/2010 - 07/2010
2NeuropeptidesIBA
10/2010 - 03/2008
2LuciferasesIBA
07/2010 - 11/2004
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
07/2010 - 07/2007
2Interleukin-10 (Interleukin 10)IBA
07/2010 - 01/2002
2Chemokine CCL5IBA
01/2010 - 07/2007
2Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA
03/2008 - 07/2007
2Collectins (Collectin)IBA
07/2007 - 01/2005
2Serum Amyloid A Protein (Serum Amyloid A)IBA
03/2006 - 01/2006
1fibrin fragment D (D-dimer)IBA
11/2022
1RetinoidsIBA
11/2022
1Angiotensin-Converting Enzyme 2IBA
01/2022
1Volatile Fatty AcidsIBA
01/2022
1Uridine Triphosphate (UTP)IBA
01/2022
1Adenosine Triphosphate (ATP)IBA
01/2022
1DNA (Deoxyribonucleic Acid)IBA
01/2022

Therapy/Procedure

7Therapeutics
01/2021 - 01/2002
1Stents
11/2022